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High-throughput analysis of subcellular localization in budding yeast [electronic resource] / Erin O'Shea. Channel: NIH Length: 4511 Date: September 16, 2008 (CIT): A fundamental goal of cell biology is to define the functions of proteins in the context of compartments that organize them in the cellular ...

From the big bang to the Nobel prize and on to James Webb space telescope [electronic resource] / John Mather. Channel: NIH Length: 3859 Date: September 16, 2008 (CIT): The history of the universe in a nutshell, from the Big Bang to now, and on to the future - John Mather will tell the story of how we got he...

Winning at losing : the art and science of long-term weight control [electronic resource] / Rena Wing. Channel: NIH Length: 0 Date: September 16, 2008

Evolution of membrane traffic : intelligent design or not [electronic resource] / Frances Brodsky. Channel: NIH Length: 0 Date: September 16, 2008 (CIT): The intracellular protein clathrin controls membrane traffic pathways that influence cell surface expression of receptors. Thus clathrin fu...

Regulation of production of IL-10 by T cells, macrophages, and dendritic cells [electronic resource] / Anne O'Garra. Channel: NIH Length: 3700 Date: September 16, 2008 (CIT): The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomed...

Regulatory circuitry of embryonic stem cells [electronic resource] / Richard A. Young. Channel: NIH Length: 0 Date: September 16, 2008

Genome-scale maps, measures, and models of mitochondrial function [electronic resource] / Vamsi Mootha. Channel: NIH Length: 3705 Date: September 16, 2008

Genetic modeling of neural tumors in mice [electronic resource] / Luis Parada. Channel: NIH Length: 3907 Date: September 16, 2008 (CIT): Neurofibromatosis Type 1 (NF1) is a dominantly inherited disease in which mutation of the NF1tumor suppressor either appears de novo or is t...

Local acts, global consequences : networks and the spread of HIV [electronic resource] / Martina Morris. Channel: NIH Length: 3761 Date: September 16, 2008 (CIT): For HIV and other sexually transmitted infections (STI), the potential for epidemic spread depends on connectivity in the underlying sexual ...

"Circuit neuromics" : the new path to understanding the genetic and neural causes of mood disorders [electronic resource] / Huda Akil. Channel: NIH Length: 0 Date: September 16, 2008 (CIT): This lecture will summarize our research aimed at understanding the biology of mood disorders, including efforts at identifying genetic vuln...

Quantitative peptidomics to define the function of endogenous neuropeptides and peptidases : implications in obesity [electronic resource] / Lloyd Fricker. Channel: NIH Length: 4909 Date: September 16, 2008 (CIT): Neuropeptides perform a large variety of functions as intercellular signaling molecules. To study peptides using "proteomic" approaches, it ...

Negative regulatory pathways controlling autoimmunity [electronic resource] / Jeffrey A. Bluestone. Channel: NIH Length: 3692 Date: September 16, 2008 (CIT): Accumulating evidence suggests that defective regulation is an essential underlying cause of autoimmunity. In the diabetes setting, the mos...

Regulation of p53 in mammalian cells [electronic resource] / Carol Prives. Channel: NIH Length: 3764 Date: September 16, 2008 (CIT): The focus of much of the work in Dr. Prives' laboratory is the functions of p53 and its negative regulator and transcriptional targ...

Probing unexpected connections between cell cycle control and pre-mRNA splicing [electronic resource] / Kathleen Gould. Channel: NIH Length: 3084 Date: September 16, 2008 (CIT): The fission yeast cdc5 gene was identified in a genetic screen for mutants defective in cell cycle progression. Since that time, our labora...

Proteomic insights into mitochondria in cardiac disease [electronic resource] / Jennifer van Eyk. Channel: NIH Length: 3769 Date: September 16, 2008 (CIT): Speaker: Jennifer van Eyk, PhD Director, The Hopkins NHLBI Proteomics Center Director, Bayview Proteomics Group Associate Professor Medic...

Hormones and breast cancer : etiology vs. ideology [electronic resource] / Robert Hoover. Channel: NIH Length: 0 Date: September 16, 2008 (CIT): We have known for over 300 years that reproductive factors in women impact their subsequent risk of breast cancer. We have had good evidenc...

HCMV persistence and latency [electronic resource] / Thomas E. Shenk. Channel: NIH Length: 3780 Date: September 16, 2008 (CIT): Human cytomegalovirus (HCMV) is a ubiquitous member of the ?-herpesvirus family. Although infection is usually asymptomatic in healthy child...

Finding function with mass spectrometry in cancer and infectious disease [electronic resource] / R. Angeletti. Channel: NIH Length: 3729 Date: September 16, 2008 (CIT): Understanding the functional implications of mass spectrometry experiments is facilitated at the first step of experimental design. Three pr...

Web-based tools for DNA and protein sequence analysis [electronic resource] / Peter FitzGerald. Channel: NIH Length: 3709 Date: September 16, 2008

Signposts along the chromosomal highway : how FtsK finds its target [electronic resource] / Carlos Bustamante. Channel: NIH Length: 4040 Date: September 16, 2008 (CIT): DNA translocases are molecular motors that move rapidly along DNA using adenosine triphosphate as the source of energy. FtsK is a membrane-b...

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