Teens Drake Parker (Drake Bell) and Josh Nichols (Josh Peck) have nothing in common -- except the same family. But together, these stepbrothers navigate with humor the awkward ups and downs of adolescence, school and family. If adjusting to their parents' (Nancy Sullivan and Jonathan Goldstein) new marriage isn't enough, the boys put up with their scheming sister, Megan (Miranda Cosgrove). But their biggest concern still remains teenage girls.