Supplements may not always be effective in treating dog arthritis, however. If the cartilage in your dog’s joints has significantly deteriorated, cartilage promoting supplements just won’t work. This is especially true if the cartilage has worn away and bone is contacting bone – one of the most painful conditions imaginable. However, supplements can help preserve whatever cartilage your dog still has, and can help stimulate joint fluid secretion and lubrication to the joints. So don’t give up on them too soon!