Ahead of the next round of talks later this month, we will be discussing the Islamic republic’s nuclear programme at the Frontline Club.Join us to discuss the state of play following diplomatic talks in Geneva between Iran and the five permanent members of the UN Security Council. What can be expected of the 25 October talks? Will re-elected president, Mahmoud Ahmadinejad respond positively to Barack Obama’s appeal to Tehran that it “unclench its fist"? Can a nuclear arms race in the Middle East be prevented?With Jon Leyne, the BBC’s Tehran correspondent who is currently in London, Julian Borger, the Guardian’s diplomatic editor, Con Coughlin, executive foreign editor of the Daily Telegraph. Following the success of September’s First Wednesday discussion on Afghanistan, Paddy O’Connell of BBC Radio 4’s Broadcasting House will be moderating the second of these dynamic debates.