One Manhattan doctor’s life is about to go south... deep south. Don't miss Hart of Dixie, coming this fall to The CW! Hart of Dixie videos: Watch Hart of Dixie full episodes, previews, clips, interviews and more video.Fast-talking New Yorker and brand new doctor Zoe Hart has it all figured out - after graduating top of her class from medical school, she'll follow in her father's footsteps and become a cardio-thoracic surgeon. But when her dreams fall apart, Zoe decides to accept an offer from a stranger, Dr. Harley Wilkes, to work with him at his small practice in Bluebell, Alabama.