Natural selection turns deadly in the mountain resort of Langdon when Amy Harding (Pamela Gridley) returns to her family’s cabin to escape a troubled past. As a fierce winter storm traps her and Marshall Clarke (Simon Bossell), a field biologist researching the strange disappearance of local wildlife, they come face to face with a family of deadly mutating predators. Now, to survive they must exterminate this new breed of cold-blooded killer that is growing ever stronger.