The first female US President Sally Sheridan is shot dead by a sniper during her Independence Day speech. Her assassin narrowly escapes the scene with his life, national security hot on his heels, or so it seems. Three months later, a wounded man is found. The young man (Stephen Dorff) cannot remember the slightest thing about his own identity. The only clue is a tattoo on his neck, "XIII". Could his lightning reflexes and killer instincts betray him as the presidential assassin that the US is desperately searching for?