This colloquia outlines the computational research methods, including multi-resolution clustering, image understanding, and non-rigid registration, that were used to rediscover the revolutionary technologies that created the first typographic print-press books. Using data analysis techniques based on high-resolution digital photography of surviving print press copies, research by Blaise Aguera y Arcas has shown that Gutenberg invented two different transitional printing technologies, both of which had apparently been forgotten by 1500. The first invention resembles a midway-point between printing and scribal practices.  The second invention, also unconventional, bears a striking resemblance to Linotype, the 19th century technology widely held to have brought printing into the modern era. From the Series:CSE Colloquia - 2005