The film follows the reboot mission of its filmmaker, Joe Cross.  One hundred pounds overweight, loaded up on steroids and suffering from a debilitating autoimmune disease, Cross is at the end of his rope. In the mirror he saw a 310-pound man, with a gut bigger than a beach ball and a future that wouldn’t end well. With one foot already in the grave, the other wasn’t far behind. With doctors and conventional medicines unable to provide a solution, Joe turns to the only option left: the body’s ability to heal itself. He trades in the junk food and hits the road with juicer and generator in tow, vowing only to drink fresh fruit and vegetable juice for the next 60 days. Across 3,000 miles Joe has one goal in mind: To get off his pills and get healthy. While talking to more than 500 Americans about food, health and longevity, it’s at a truck stop in Arizona where Joe meets a truck driver who suffers from the same rare condition. Phil Staples is morbidly obese weighing in at 429 pounds. He is a cheeseburger away from a heart attack. As Joe is recovering his health, Phil begins his own epic journey to get well. What emerges is nothing short of amazing - an inspiring tale of healing and human connection. Part road trip, part self-help manifesto, FAT, SICK & NEARLY DEAD defies the traditional documentary format to present an unconventional and uplifting story of two men from different worlds who each realize that the only person who can save them is themselves.