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Non-linear Elimination and Dosage Regimen
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Non-linear Elimination and Dosage Regimen
For drugs which exhibit non-linear metabolism within their therapeutic range can be difficult to dose. Small changes in dose can result in larger changes in concentration. Using average value for parameters can be a good start but better results can be achieved with therapeutic drug monitoring. Analysis of TDM data can by use of equations or graphical methods. Both types of approaches are described in this tutorial.
Video Length: 296
Date Found: May 21, 2008
Date Produced: May 17, 2008
View Count: 14
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