After abandoning a promising academic career in forensic science, aimless Doug returns to Portland to live with his more responsible big sister Gail. He easily lands a dead-end job working in an ice factory, but his latent passion for detective work is stoked when his ex-girlfriend, Rachel goes missing. Armed with a handful of arcane clues and a vast knowledge of the world of Sherlock Holmes, Doug enlists Gail and co-worker Carlos in a ramshackle investigation that draws the slacker sleuths into Portland’s underground. What they discover is a complex trail of clues, leading them increasingly close to the discovering the mysterious truth about Rachel.