(CIT): This joint NIH/NIDA/AMA meeting will bring together the research and clinical practice communities through its co-sponsorship with the AMA, and supported by the NIH Pain Consortium to draw attention to the growing problem of prescription opioid misuse by patients with chronic non-malignant pain conditions. The most powerful treatments available for most forms of pain are opioids. However, opioid treatment can produce negative health consequences, such as intoxication and physical dependence, and may result in opioid abuse and addiction. The prevalence of, and the process of how to prevent, reduce and treat these negative health consequences are not well understood. The goal is to inform practitioners and scientists on emerging research on pain and addiction and what we are learning about how to most effectively and compassionately treat these conditions, while minimizing the risk of abuse and addiction.