Dr Bertolini speaks to ecancer.tv about his research into anti-angiogenic therapy as treatment for breast cancer. Anti-angiogenic therapy has been successful increasing progression free survival, but has not yet achieved an increase in overall survival. Dr Bertolini’s team is now looking to see how the combination of chemotherapy and anti-angiogenic therapy can be improved and are also working with surrogate biomarkers to identify which patients are suited to particular treatments.