Mashable’s Editor in Chief, Adam Ostrow, and the host of NBC's ""Poker After Dark,"" Ali Nejad, riff on the Mario Lopez-wearing-Screech-wearing-Tiffani-Amber Thiessen-wearing-Bieber (and all other variations of) meme on the Like/Dislike segment of the What's Trending live show. We also discuss Twitter's addition of in-stream ads, graphic pictures being added to U.S. cigarette boxes and Sad Keanu's uplifting poetry. (July 28, 2011)