The Co-Chairs (Dr Ken Anderson, Dr Jesus San Miguel, Dr Nikhil Munshi, Dr Keith Stewart) of the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics discuss the highlights of the meeting, focussing on the genetics and pharmacogenomics of multiple myeloma and the new and emerging therapies.The workshop was supported by an unrestricted medical education grant from the following companies; Celgene, Bristol Myers Squibb, Johnson and Johnson, Takeda Millennium, Novartis Oncology, Cephalon and Onyx Pharmaceuticals.