Continuing on from the first season, Zoku Natsume Yuujinchou follows the story of Natsume, a boy who has been able to see ghosts since he was little. Unfortunately, humans shun him, and there is not much fondness between him and ghosts either. One day, he inherits a Y?jin-Ch? ("Book of Friends") from his grandmother. The book is actually full of contracts that his grandmother made to trap ghosts. As one ghost after another shows up, Natsume tries to release or help them ? even while many of them seek vengeance on him.